
Future of your Business, Family and Wider World by Dr Patrick Dixon, Futurist Speaker, Keynotes on Growth Strategies and Leadership, Lecture Slides, Articles and Videos from Conferences - 15 million unique visitors to MAIN Futurist site (articles / keynotes / videos) - link on right to www.globalchange.com
February 01, 2013
January 30, 2013
December 23, 2012
How Oncolytic Viruses Kill Cancer Cells: research, trials, cancer treatm...
How Oncolytic Viruses Kill Cancer Cells: research, clinical trials, cancer treatment, possible cure for cancer
More: http://www.virttu.com . How oncolytic viruses work to kill cancer cells in melanoma, head and neck, prostate cancer and glioblastoma brain timours. Replication of oncolytic viruses inside tumours. Pre-clinical trials. Phase I, Phase II and Phase III clinical trials on oncolytics. Use of oncolytic viruses to treat advanced malignant melanoma and mestatases – Amgen research using an oncolytic virus developed from HSV (Herpes Simplex Virus). Problems with traditional chemotherapy – side effects. Why Amgen bought an oncolytic viruse for $500m in cash and $500m to be paid if oncolytic trials are fully successful. Investor interest in oncolytic viruses. Lessons from the history of research and development in monoclonal antibodies in cancer treatment. Why targeted cancer therapy – a so-called “magic bullet” is so needed. How oncolytic viruses have been modified so that they cannot replicate in normal cells, but are still able to divide in a wide variety of human cancer cells. History of oncolytic viruses. Arming oncolytic viruses. Using viruses like Seprehvir (HSV-1716), adapted to carry an additional payload: extra genes which teach infected cancer cells to take up a compound containing radioactive iodine from the blood, delivering a micro-dose of radiation inside individual cancer calls. Or adding a gene which teaches cancer cells how to split a harmless pro-drug into two, inside the cell, releasing a very toxic chemo (alkylating agent). Targetting oncolytic viruses – by adapting the feet of a virus to that they latch onto receptors on the surface of specific human cancer cells such as prostate. Results of early Phase III Rheolysin clinical trials – combined oncolytic virus and cancer chemotherapy. Side effects and safety profile of oncolytic viruses in clinical studies. FDA safety review of oncolytic viruses and approval for systemic administration of oncolytic viruses to children with advanced cancer. How genes work in viruses, and how genetic engineering allows us to cut and paste genes from one species into another. Patrick Dixon author of The Genetic Revolution, Chairman of Global Change Ltd, an advisor to many large pharma companies and to Virttu Biologics Ltd.
November 14, 2012
May 11, 2012
May 03, 2012
March 25, 2012
Future of Music - the secret of great music - music physics, performance...
What exactly is music? The secret of great music. Physics of sound and how it communicates. How all great music connects with passion and all great performers provoke a response from those who listen. The elusive magic of a world class musician and why live performance will become increasingly important in a virtual, online world. Future of the Music Industry. Comment by Dr Patrick Dixon, futurist, leading authority on global trends, conference speaker -- (bad) player of many different instruments and amateur composer.
March 23, 2012
November 15, 2011
As a Futurist: Optimist or Pessimist? Personal view of future world - co...
As a Futurist, why I am an optimist about our ability to transform our future world in a positive and sustainable way. Part of keynote on the $40 trillion green tech revolution which could transform the future of our planet
Building a Better World: ultimate mission and brand value. Motivational ...
Change your life and strengthen your business. Building a Better Business by building a better world. Show how you make a difference in the lives of your customers, clients, consumers. Leadership - motivational leadership styles, leadership skills, leadership quotes, management tools. Biggest ethical test for every culture and every nation: creating a better world, improving life for people. Core value to drive every political debate, underwrites all laws, basis of all team leadership impossible to lead effectively for long without this principle: will the world be a better place as a result of this activity or not? Key to management, marketing, brands, branding, corporate image, reputation and motivation. Applies to leadership and team management in every industry including banks, banking, retail, communication, technology, phone companies, logistics, travel, tourism, freight, manufacturing, health care, pharmaceutical industry, innovation, product development, research, construction, real estate investment, fund management, investment banking and energy, transport and aviation. Whose world? Fundamental principle. If everyone or every business followed this example, would the world be a better place? Define better and world. Example in pharmaceutical industry failure to adequately protect their own patents and intellectual capital in face of public criticism about global health inequalities and social justice. Failure by pharma industry to win the better world argument in media. The most important promise of every business: we will make life better at a price you can afford. Human resources, team motivation, staff engagement and customer engagement. Impact on marketing and customer relationship management, customer satisfaction surveys. How to win war for talent, encourage recruitment, reduce staff turnover, increase staff retention. Executive education and staff training in leadership. The purpose: deliver on the promise. Profit comes from delivering on the promise. Part of keynote on the $40 trillion green tech revolution which could transform the future of our planet, with innovations that will provide answers to global warming if rolled out on a large enough scale. Impact of technologies already available in energy industry, water conservation, carbon reduction, recycling, power transmission over long distances, alternative power generation, buildings management. Conference keynote speaker and Futurist Patrick Dixon -- author of SustainAgility book, lecture for Suez Environmental global leadership team.
How to solve global water crisis: Innovation, Green Technology. Water, U...
How global water shortages will be solved. Drought in Australia, America, Asia, China, Africa, Australia. Crop failures, food price rises, hunger and famine. Forest fires and other results of lack of rain. Virtual water -- water used in energy production, manufacturing, agriculture, farming, food production and processing, textiles, pulp and paper industry. River management, with diversions and dam building is only part of solution. Expect huge growth in water conservation in agriculture and manufacturing. Virtual water and water trading as part of the globalisation of products and food. Link between water use and energy generation -- power station cooling for example. How low cost energy could solve water shortages by reducing cost of next-generation desalination. Part of keynote on the $40 trillion green tech revolution which could transform the future of our planet, with innovations that will provide answers to global warming if rolled out on a large enough scale. Impact of technologies already available in energy industry, water conservation, carbon reduction, recycling, power transmission over long distances, alternative power generation, buildings management. Conference keynote speaker and Futurist Patrick Dixon -- author of SustainAgility book, lecture for Suez Environmental global leadership team.
Euro crisis and Revolution - risks to your business, family and wider wo...
Euro collapse, government debt defaults, risks in Greece, Italy, Spain, Portugal, Ireland. Risks to Eurozone, action by European Central Bank (ECB). Risk to Europe and government instability, protests, riots, civil disorder, fall of government, tension between nations, revolution, war. European Union was created out of the ashes of two World Wars with a big aim to help ensure peace. Video keynote conference presentation by Futurist Patrick Dixon
November 11, 2011
Marketing Strategy - multichannel mix. Future messages. Marketing trends...
Future marketing strategy is more than about altering a marketing mix for multichannel customers. Marketing needs to change values as well as messaging in a world dominated by instant information and insight / feedback from our online friends and extended social networks. It means an end to hype and spin or exaggerated claims, and a focus on what is true, valid claims, accurate information, detailed feedback from real customers, genuine facts, verifiable data. This a post-marketing world: in the last century, the source of most customer information about products or services came from the marketing team itself. Today, most of the information that a customer ever learns about what you want to sell them is probably coming from other sources. That means we need to completely rethink how we position marketing messages. The very word "marketing" needs rethinking. The future is about personalized, insightful, timely, accurate, sensitive and intuitive advice along the journey of life. Conference keynote speaker and futurist Patrick Dixon, speaking to retail clients of Hermes in the UK on the future of marketing to retail customers.
New markets: older customers - ageing population in Europe / EU. Retail ...
Why older customers are an important retail market for consumers. Meeting the needs of older shoppers in design and layout of stores, shopping malls, and in signage. Most people over 50 cannot read small type without glasses yet most printed material used in marketing is designed for younger eyes. Conference keynote speaker on retail and consumer trends - Futurist Patrick Dixon lecture for Hermes retail clients in the UK.
Growth of Budget Brands AND Super Premium. Retail industry trends - Futu...
How sales of budget brands AND super-premium brands are both set to grow. Future of retail industry and trends in sales of luxury goods and services. Economic crisis, austerity, fall in personal disposable income, increase in taxation, rise in unemployment, cuts in government spending. All these economic factors will force more people to buy budget brands. However, expect the wealth gap between the rich and poor to increase in every nation, especially growth in the numbers of super wealthy consumers. These ultra high net worth consumers will drive sales of luxury, premium, rare and exotic items, fast cars, super yachts, private jets, huge properties, exquisite jewelry, privileged access to unique experiences. Impact on marketing strategy and selling techniques. Re-positioning of key brands -- up market and down market, chasing revenues. Patrick Dixon is a trends analyst, Futurist conference keynote speaker on a wide range of global trends including retail industry, consumer insight. Keynote lecture for retail clients of Hermes in the UK.
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