January 22, 2014

Global Economic Outlook, impact of emerging markets -- Global Economy co...

http://www.youtube.com/watch?v=v7WA3MuIH4s

Impact of emerging markets on growth of global economy. Economic outlook for
EU, US, Asia and Latin America and why business leaders in developed nations
often have a distorted view of true global economic growth and future economic
recovery.  Keynote conference speaker
Patrick Dixon, lecture on global economy and business travel for American
Express (Amex) and TAP Moscow.  Why we
need to focus on China and countries like Vietnam.  Why news media are unrealiable guide to the
truth about global economic growth.
Beyond the downturn, predicting timing of global recovery.  Risks of inflation, deflation, boom and bust,
double-dip recession, and impact of rapid changes in interest rates, actions by
central banks, stimulating money supply, printing money, quantitative easing –
but the fact is that the entire global economy grew throughout the huge economic
crisis of 2008-2013, and the crisis had very different impacts on countries
like India or Portugal.  Expect
spectacular growth of aviation and rail travel in emerging economies such as
China and India.  The irresistible human
desire to travel, explore, and gain new experiences will underpin consistent
global growth in travel and tourism, despite new carbon and aviation
taxes.

Agile Leadership: strategy overtaken by events, need for scenarios etc

Why we need agile leadership: corporate strategy is often overtaken by
events.  Need for smarter forecasting, faster strategic thinking, more agile leadership, dynamic teams, faster change management programmes. Keynote on Managing Uncertainty and risk management. Why boards need more than one strategy. Scenario planning, forecasting.
Corporations are vulnerable to major shocks – political, global economy,
environment, climate change or other factors ranging from volcanic eruptions to
the Arab Spring, or disruptions to supply chains, logistics failures, manufacturing
disruption, unexpected competitor action or product innovation. Example: impact
of energy prices on future of aviation and global travel. Keynote on leadership
and future travel industry trends for American Express / TAP in Moscow, by
Patrick Dixon, conference speaker.  Future of hotels, airlines and travel agents – innovation in the travel industry.  Future of business travel and leisure travel.


February 06, 2013

Future of Telcos - why business models broken. Telecom mobile customer t...

Future of telecom companies and smartphones, mobile devices and why the telecom business model is broken.  Patrick Dixon conference keynote speaker on telco issues and customer experience. Where will future telecom revenues come from and risks to future strategy.  Future customers will be even more impatient about waiting for -- web pages to load, calls to be answered, software to update, mobile devices to reset.  Future of customer services and customer relationship management. Technology convergence or divergence and why all innovation is divergent.  Ethical issues when companies sell hardware or software that they know contains significant bugs eg failure to reliably synchronise PC and phone data.  Why risky to believe results of market research as guide to future trends -- because customers change rapidly.  Converging on features, quality and price results in spiral to bottom on profits and return on equity.  Cloud-based computing and impact of cloud software on enterprise system design.  New revenue models for telecom companies -- enterprise solutions, cloud-based data management, mobile payments and financial services.  90% of all Microsoft R&D is cloud-related in some way. Radical opportunities to provide free mobile devices, handsets, ipads etc, bandwidth, calls, SMS and online content, free storage of photos and movies in the cloud, in return for agreement to use mobile device almost exclusively for card transactions.  Paid for by commissions on mobile transactions charged to retailers, and also by charges for credit, loans, insurance and related financial products. Biometric mobile payments -- using screen detection of fingerprints.  Most debates about future are about timing of predictable events -- eg date by which costs of mobile devices falls so low that they can be provided for free by a financial institution.  Impact of regulation and compliance.  Why bandwidth use will be dominated by video -- which already consumes more than 70% of all bandwidth in some European nations. Impact of YouTube and BBC iplayer in the UK.  Why telcos are being overtaken by video streaming as primary use of mobile and landline data. Dwarfing all voice calls, SMS, emails etc.  Geopositioning and multichannel marketing, impact of Big Data on smart direct marketing campaigns.  RFID tags in the internet of things.  Concerns about privacy from data harvesting of consumer information to produce accurate insights about future purchasing decisions.  Impact on mass market, fast moving consumer goods (FMCG).  Future of Google and other search engines and impact of social networks such as Facebook and Twitter on future search listings, and what appears on Google Pay per Click adverts.  How social network recommendations are winning trust over corporate websites, and why sites like TripAdvisor are dominating consumer decisions.  Winning trust, or restoring trust, is the most important challenge facing many corporations.  The only product or service a bank sells is trust and without trust you have no bank.  Without trust, it may be that you have no government either.  Why opinions of complete strangers are more influential over most consumers in some industries than official marketing information.  Why traditional marketing is dead in the third millennial, multi-dimensional online world.  Video recorded in 2012 for global leaders of enterprise technology and innovation for one of the world's largest telecom companies.

December 23, 2012

How Oncolytic Viruses Kill Cancer Cells: research, trials, cancer treatm...





How Oncolytic Viruses Kill Cancer Cells: research, clinical trials, cancer treatment, possible cure for cancer

More: http://www.virttu.com . How oncolytic viruses work to kill cancer cells in melanoma, head and neck, prostate cancer and glioblastoma brain timours. Replication of oncolytic viruses inside tumours. Pre-clinical trials. Phase I, Phase II and Phase III clinical trials on oncolytics. Use of oncolytic viruses to treat advanced malignant melanoma and mestatases – Amgen research using an oncolytic virus developed from HSV (Herpes Simplex Virus). Problems with traditional chemotherapy – side effects. Why Amgen bought an oncolytic viruse for $500m in cash and $500m to be paid if oncolytic trials are fully successful. Investor interest in oncolytic viruses. Lessons from the history of research and development in monoclonal antibodies in cancer treatment. Why targeted cancer therapy – a so-called “magic bullet” is so needed. How oncolytic viruses have been modified so that they cannot replicate in normal cells, but are still able to divide in a wide variety of human cancer cells. History of oncolytic viruses. Arming oncolytic viruses. Using viruses like Seprehvir (HSV-1716), adapted to carry an additional payload: extra genes which teach infected cancer cells to take up a compound containing radioactive iodine from the blood, delivering a micro-dose of radiation inside individual cancer calls. Or adding a gene which teaches cancer cells how to split a harmless pro-drug into two, inside the cell, releasing a very toxic chemo (alkylating agent). Targetting oncolytic viruses – by adapting the feet of a virus to that they latch onto receptors on the surface of specific human cancer cells such as prostate. Results of early Phase III Rheolysin clinical trials – combined oncolytic virus and cancer chemotherapy. Side effects and safety profile of oncolytic viruses in clinical studies. FDA safety review of oncolytic viruses and approval for systemic administration of oncolytic viruses to children with advanced cancer. How genes work in viruses, and how genetic engineering allows us to cut and paste genes from one species into another. Patrick Dixon author of The Genetic Revolution, Chairman of Global Change Ltd, an advisor to many large pharma companies and to Virttu Biologics Ltd.

March 25, 2012

Future of Music - the secret of great music - music physics, performance...


What exactly is music? The secret of great music. Physics of sound and how it communicates. How all great music connects with passion and all great performers provoke a response from those who listen. The elusive magic of a world class musician and why live performance will become increasingly important in a virtual, online world. Future of the Music Industry.  Comment by Dr Patrick Dixon, futurist, leading authority on global trends, conference speaker -- (bad) player of many different instruments and amateur composer.

November 15, 2011

As a Futurist: Optimist or Pessimist? Personal view of future world - co...



As a Futurist, why I am an optimist about our ability to transform our future world in a positive and sustainable way. Part of keynote on the $40 trillion green tech revolution which could transform the future of our planet

Building a Better World: ultimate mission and brand value. Motivational ...



Change your life and strengthen your business. Building a Better Business by building a better world. Show how you make a difference in the lives of your customers, clients, consumers. Leadership - motivational leadership styles, leadership skills, leadership quotes, management tools. Biggest ethical test for every culture and every nation: creating a better world, improving life for people. Core value to drive every political debate, underwrites all laws, basis of all team leadership impossible to lead effectively for long without this principle: will the world be a better place as a result of this activity or not? Key to management, marketing, brands, branding, corporate image, reputation and motivation. Applies to leadership and team management in every industry including banks, banking, retail, communication, technology, phone companies, logistics, travel, tourism, freight, manufacturing, health care, pharmaceutical industry, innovation, product development, research, construction, real estate investment, fund management, investment banking and energy, transport and aviation. Whose world? Fundamental principle. If everyone or every business followed this example, would the world be a better place? Define better and world. Example in pharmaceutical industry failure to adequately protect their own patents and intellectual capital in face of public criticism about global health inequalities and social justice. Failure by pharma industry to win the better world argument in media. The most important promise of every business: we will make life better at a price you can afford. Human resources, team motivation, staff engagement and customer engagement. Impact on marketing and customer relationship management, customer satisfaction surveys. How to win war for talent, encourage recruitment, reduce staff turnover, increase staff retention. Executive education and staff training in leadership. The purpose: deliver on the promise. Profit comes from delivering on the promise. Part of keynote on the $40 trillion green tech revolution which could transform the future of our planet, with innovations that will provide answers to global warming if rolled out on a large enough scale. Impact of technologies already available in energy industry, water conservation, carbon reduction, recycling, power transmission over long distances, alternative power generation, buildings management. Conference keynote speaker and Futurist Patrick Dixon -- author of SustainAgility book, lecture for Suez Environmental global leadership team.